The first four weeks of the 2025-26 NFL season were mostly fun and games, as long as your team has secured at least two wins so far. But now, things start to get a little more serious in October.

The Tampa Bay Buccaneers have all but lost their season at 0-4, but Dak Prescott and the 2-2 Dallas Cowboys need a Thursday Night Football win to keep the pace in the NFC East.

Sunday is jam-packed with good games, but the three I would watch most closely are:

  • 4-0 San Francisco 49ers at 3-1 Seattle Seahawks in the Sakmann Sports Game of the Week: this one will settle the debate, temporarily, of who the strongest team in not just the NFC West but the entire NFC is.
  • The 3-1 Las Vegas Raiders look to bounce back from their first loss of the season, a super competitive loss to the Kansas City Chiefs, while Drake Maye and the 2-2 New England Patriots look to put their early season struggles in the rearview mirror and emerge from Week 5 with a record above .500.
  • 2-2 Indianapolis Colts at 2-2 Pittsburgh Steelers doesn’t seem high stakes, but could easily set a trend for which team will be more competitive in the AFC this season, or even a potential playoff seeding tiebreaker if both teams remain in the mix.

On Sunday Night Football, the 2-2 Atlanta Falcons make their third straight primetime appearance, hosting Lamar Jackson and the 3-1 Baltimore Ravens.

Then to round out the week, Josh Allen and the 3-1 Buffalo Bills take on Matthew Stafford and the 2-2 Los Angeles Rams in what should be a great matchup. Can the Bills beat the Rams in their own house to send the Super Bowl 56 hopefuls to 2-3? Or will Los Angeles bounce back and get a much-needed win to keep up in the NFC West?

Read on for my 2026-27 NFL Week 5 Picks and be sure to follow Sakmann Sports on Twitter/X or on Facebook for more!

Picks Record

Week 1: 11-5

Week 2: 12-4

Week 3: 6-10

Week 4: 11-5

Thursday Night Football

(ESPN)

Tampa Bay Buccaneers (0-4) at Dallas Cowboys (2-2): Cowboys win 24-20

Sunday Games

(NFL.com)

Game in London Philadelphia Eagles (2-2) at Jacksonville Jaguars (3-1): Jaguars win 31-20

Cleveland Browns (3-1) at New York Jets (1-3): Browns win 27-16

Chicago Bears (3-1) at Green Bay Packers (2-2): Bears win 20-16

Cincinnati Bengals (2-2) at Miami Dolphins (0-4): Bengals win 26-17

Minnesota Vikings (4-0) at New Orleans Saints (1-3): Vikings win 24-20

Houston Texans (0-4) at Tennessee Titans (0-4): Texans win 20-10

New York Giants (3-1) at Washington Commanders (1-3): Commanders win 24-22

Las Vegas Raiders (3-1) at New England Patriots (2-2): Patriots win 27-23

Indianapolis Colts (2-2) at Pittsburgh Steelers (2-2): Steelers win 24-17

Denver Broncos (2-2) at Los Angeles Chargers (0-4): Broncos win 23-20

Detroit Lions (2-2) at Arizona Cardinals (1-3): Cardinals win 30-24

Sakmann Sports Game of the Week San Francisco 49ers (4-0) at Seattle Seahawks (3-1): 49ers win 24-21

Sunday Night Football

(NBC4 Washington)

Baltimore Ravens (3-1) at Atlanta Falcons (2-2): Ravens win 30-20

Monday Night Football

(NY Times)

Buffalo Bills (3-1) at Los Angeles Rams (2-2): Rams win 30-23

Teams on Bye

Kansas City Chiefs (4-0), Carolina Panthers (2-2)

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Header Photo Credit: NBC4 Washington

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Posted on 0 By Billy Sakmann NFL Posted in NFL, Sakmann Sports Tagged #, , , , , , , , , , , , , , , , , ,
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